TY - JOUR
T1 - Five new alkaloids from the leaves of Remijia peruviana
AU - Díaz, Jesús G.
AU - Sazatornil, José Gavin
AU - Rodríguez, Matías López
AU - Mesía, Lastenia Ruiz
AU - Arana, Gabriel Vargas
PY - 2004/10
Y1 - 2004/10
N2 - Three new indolylquinuclidine-type alkaloids, remijinine (1), epiremijinine (2), and 5-acetyl-apocinchonamine (3), and two new cinchonine-derived alkaloids, N-acetyl-deoxycinchonicinol (4) and N-acetyl-cinchonicinol (5), as well as the known alkaloids quinamine, conquinamine, cinchonine, and quinidine were isolated from the leaves of Remijia peruviana. The structures of the new alkaloids were elucidated on the basis of spectroscopic analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HMQC, and HMBC). The relative configuration at C-7 for remijinine (1) and, in consequence, for epiremijinine (2) was established by X-ray crystal structure analysis of the former.
AB - Three new indolylquinuclidine-type alkaloids, remijinine (1), epiremijinine (2), and 5-acetyl-apocinchonamine (3), and two new cinchonine-derived alkaloids, N-acetyl-deoxycinchonicinol (4) and N-acetyl-cinchonicinol (5), as well as the known alkaloids quinamine, conquinamine, cinchonine, and quinidine were isolated from the leaves of Remijia peruviana. The structures of the new alkaloids were elucidated on the basis of spectroscopic analysis, including homonuclear and heteronuclear correlation NMR experiments (COSY, ROESY, HMQC, and HMBC). The relative configuration at C-7 for remijinine (1) and, in consequence, for epiremijinine (2) was established by X-ray crystal structure analysis of the former.
UR - http://www.scopus.com/inward/record.url?scp=7044240925&partnerID=8YFLogxK
U2 - 10.1021/np040053k
DO - 10.1021/np040053k
M3 - Article
C2 - 15497937
AN - SCOPUS:7044240925
SN - 0163-3864
VL - 67
SP - 1667
EP - 1671
JO - Journal of Natural Products
JF - Journal of Natural Products
IS - 10
ER -