Indole alkaloids from Aspidosperma rigidum and A. schultesii and their antiparasitic effects

Matías Reina, Wilfredo Ruiz-Mesia, Lastenia Ruiz-Mesia, Rafael Martínez-Díaz, Azucena González-Coloma

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

24 Citas (Scopus)

Resumen

Five oxindole alkaloids, three plumerane-type alkaloids, subtype haplophitine, and one aspidospermatane-type alkaloid, subtype tubotaiwine, were isolated from the medicinal plants Aspidosperma rigidum and A. schultesii. One compound was identifi ed as the transoid conformer of 18-oxo-O-methylaspidoalbine which was not previously described. The antiparasitic activity of all compounds against Trypanosoma cruzi and Leishmania infantum and their non-specifi c cytotoxicity against mammalian cells were also determined.

Idioma originalInglés
Páginas (desde-hasta)225-234
Número de páginas10
PublicaciónZeitschrift fur Naturforschung - Section C Journal of Biosciences
Volumen66 C
N.º5-6
DOI
EstadoPublicada - 2011

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